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Mesothelioma and Asbestos Exposure Mesothelioma can be caused by exposure to asbestos. Exposure to asbestos can happen at work or at home. The symptoms of pleural mesothelioma are coughing, chest pain and dry cough. Other symptoms include abdominal pain, fluid buildup and testicular carcinoma. There are four types of mesothelioma. The most common is called pleural mesothelioma. Workplace Exposure Mesothelioma is a cancer that affects the tissues of certain organs, like the lungs or the abdomen, is usually caused by exposure to asbestos. This toxic mineral is used in many industries and, when it breaks down, creates a fine dust that can be inhaled or consumed. Many occupations historically have involved the exposure of workers to asbestos. This includes asbestos insulation workers, plumbers, electrical engineers, shipyard employees, and producers of automotive components brake pads, clutches and clutches. Construction workers who are exposed to asbestos through their building materials, or while tearing down old buildings face the risk of exposure. When mesothelial cell mutations happen, they can grow uncontrollably and form tumors which spread throughout the body. Mesothelioma is most often found in the abdomen or lungs however it can also be found in other organs, such as the testicles and the heart. There are various types of mesothelioma. Each type is named after the organ that it affects. Symptoms of mesothelioma usually appear 30 to 50 year after the first exposure. Mesothelioma can be a rare cancer, which can be difficult to detect. It could take a long time for symptoms to be evident. Asbestos sufferers must seek medical help to be diagnosed and receive treatment. Non-occupational asbestos exposure may increase mesothelioma risk. Indirect or secondary asbestos exposure occurs when people come into contact with asbestos fibers through contaminated clothing or household items. These contacts may occur when family members wash and clean one's work clothes, or when a person lives within the vicinity of an industrial asbestos source. A few studies that are based on population-based case-control have examined asbestos exposure in para-occupational settings and mesothelioma-related risk. One study showed mesothelioma risks that were significant for residents living close to an asbestos cement plant in Casale Monferrato, northwest Italy. The authors attributed the rise in mesothelioma risks due to the proximity of homes to the plant and exposure to the air from the use of asbestos cement products on nearby roads and structures. Similar results have been observed in other community-based studies that have clearly identified industrial sources for para-occupational exposure. However these studies are difficult to conduct. Some studies have had difficulty separating out individuals with known occupational or para-occupational exposure to asbestos which could cause them to make errors in assessing the mesothelioma risk of those individuals. Environmental Exposure Asbestos is a class of minerals with microscopic, thin fibers. Because they are resistant to fire, chemicals and electricity, asbestos has been employed in a variety of industrial processes and products. Mesothelioma is more likely to develop in people who work with asbestos or are exposed to it in other ways. This includes asbestos miners, shipyard workers, asbestos cement manufacturers and insulators. Mesothelioma also gets found in hair and clothing of asbestos workers, putting their family at risk. The primary cause of mesothelioma lies in occupational exposure to asbestos. However, a small number of cases have been reported in patients who had non-occupational (para-occupational) exposure to asbestos. In these cases, asbestos fibers could have entered the lungs or digestive tract through air contamination, or by eating food contaminated with asbestos. Typically, these mesothelioma-related cases have occurred in the family members of asbestos-exposed workers. The diagnosis of mesothelioma usually made decades after asbestos exposure. Tumors are typically found in the chest and abdomen. The most common type of mesothelioma is mesothelioma of the pleura which affects the chest cavity's lining. The peritoneum is the lining for your abdominal cavity. It is the second most commonly-used mesothelioma that is malignant. The mesothelioma cancer cells are classified as epithelioid or even sarcomatoid. Epithelioid mesothelioma is responsible for 60 70 to 80 percent of all mesothelioma cases, and generally has the highest success rate. Sarcomatoid Mesothelioma is more aggressive, and has a less favorable prognosis. Biphasic mesothelioma is a form that occurs in 10 to 15 percent of patients. It combines epithelioid cells with sarcomatoid cells. Men are more likely to develop mesothelioma compared to women. The majority of patients diagnosed with the disease were exposed to asbestos at work. However, the reasons for this gender difference remain elusive. It could be related to the higher percentage of men employed in industries that commonly employed asbestos, such as construction and manufacturing. Numerous studies have revealed elevated mesothelioma rates in communities or regions with multiple asbestos-related industrial sources. Visalia asbestos attorneys of mesothelioma in 70 communities that were contaminated with Vermiculite from the Libby Asbestos Mine in Montana found that people who lived within 2000m of these facilities had a greater risk of mesothelioma. Genetic Predisposition In some instances genetics play a significant role in mesothelioma. The condition is believed to be linked to hereditary gene mutations that interfere with DNA repair mechanisms. Researchers have identified genes that might make a patient more susceptible to mesothelioma. Some studies have demonstrated that people with a family history of mesothelioma are more likely to develop mesothelioma than those who do not have any family history. The mechanism behind the disease isn't fully understood. It is well-known that occupational and environmental asbestos exposure can lead to the disease. However, not every person exposed to asbestos develops mesothelioma. Certain mesothelioma patients have not been exposed to asbestos, while those who have experienced extensive occupational exposure never develop this disease. Patients who are exposed to asbestos are likely to have genetic mutations which interfere with the repair of DNA. A genetic mesothelioma test used to determine whether an individual is affected by hereditary mutations in the gene that could increase their risk of developing the disease. The test can be performed by a doctor who takes a sample from saliva or blood. The sample is sent to a laboratory to be tested. Most of the time the results of the test are available within two weeks. Some families with multiple mesothelioma patients have a mutation in the gene BAP1. This gene is involved with repair of damaged DNA. The mutation can cause cancerous cells to become over-produced which then spread to other parts of your body, causing mesothelioma. The genetic mesothelioma test is a valuable tool for identifying asbestos-related diseases. They can assist doctors know the causes of mesothelioma and develop more effective treatment plans. Avoiding exposure to asbestos in the workplace and in the environment can help prevent exposure to asbestos that is not intended for. Talk to your doctor in the event that you have a family history of mesothelioma. Some people may also benefit by participating in mesothelioma testing programs that require an swab of the cheek or blood sample. A team of experts evaluates the mesothelioma diagnose of a patient in these programs. The mesothelioma treatment plan for the patient is then designed in accordance with their specific diagnosis. Treatment Mesothelioma develops when minuscule asbestos fibers enter the body and cause damage that eventually leads to cancer. Asbestos exposure can occur in many ways, including when employees take asbestos pieces apart to remove it or when people carry asbestos fibers home on their skin and clothing after they leave work. These fibers can enter the stomach and lungs where they can cause irritation, which causes cancer. Symptoms of mesothelioma don't appear for 20 to 50 years after exposure, therefore it is crucial that those who may have been exposed to asbestos visit their doctor immediately. Most mesothelioma patients are male and the most prevalent form of the disease is one that affects the linings of the lungs (pleural mesothelioma). Other types of mesothelioma can be found in the stomach's lining, the peritoneum, or the lining of the heart or testicles. As with all forms of cancer, mesothelioma is when cells start to grow out of control and form a tumor. The abnormal cells can expand to other parts of the body, and eventually cause more cancerous tumors to form. Researchers do not fully understand the causes of mesothelioma. However, they know that asbestos exposure is an important risk factor. Patients suffering from mesothelioma are usually treated with chemotherapy and surgical procedures to stop the progression of their condition. It is crucial for those who have been exposed to asbestos to monitor their health and talk to their physicians about their work history. Mesothelioma patients should undergo regular screenings for evidence of asbestos as well as other potential problems. Mesothelioma can be characterized by pain and fluid buildup around the lungs. Other symptoms can include chest pain, coughing as well as an ache on the chest and abdomen abdominal swelling, difficulty breathing weight loss, fatigue and fever. Symptoms can be similar to other illnesses and conditions, so mesothelioma is sometimes wrongly diagnosed. X-rays and blood tests can confirm the diagnosis. Some mesothelioma patients might have genetic mutations in their DNA, which increase their chances of developing this disease. These patients should consult their doctor about genetic counseling.